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None of that applies to vials sold online as "research use only." Independent lab testing across online peptide vendors has found that approximately 8% of all samples tested contained measurable endotoxins bacterial fragments that can cause fever, chills, or septic shock at higher concentrations
Large-scale CRISPR-based screens have identified thousands of degron motifs, particularly at protein C-termini, regulated by Cullin-RING E3 ligase complexes such as CRL2 and CRL4
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