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Clinical research has focused on its applications for reducing visceral fat and improving body composition in specific research populations, including studies on HIV associated lipodystrophy

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The EMPEROR-Reduced trial included patients with HFrEF, both with and without diabetes mellitus, who had NYHA class IIIV, LVEF 40% despite OMT, and eGFR 20 ml/min/1.73 m 2