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JAMA Intern Med (2013) 173(7):5349

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doi: 10.1007/s13181-013-0310-2

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328 Although setbacks occurred in the phase II study, the combination of ADI-PEG-20 and mFOLFOX6 chemotherapy regimen did not show a significant therapeutic advantage for hepatocellular carcinoma, 239 but there are a small number of subjects who benefit from this regimen