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Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-L-histidyl-L-lysine copper
Hennige, A.M
Synergistic pathway activation BPC-157 activates the VEGFR2-Akt-eNOS axis
Wei and colleagues (Wei et al., 2022) recently discovered that GLP-1 receptor activation inhibits this signaling pathway by modulating ROCK activity, leading to a reduction in the phosphorylation of MLC, which stabilizes the endothelial cell cytoskeleton and tight junctions by upregulating the expression of tight junction proteins such as Occludin and ZO-1
Metoclopramide may be considered for short-term use only (generally less than 12 weeks) due to the risk of tardive dyskinesia with prolonged use
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