Whilst gastrointestinal symptoms such as nausea, vomiting, and diarrhoea are the most commonly reported adverse effects according to the Summary of Product Characteristics (SmPC), some patients report musculoskeletal symptoms, including body aches, although these are not listed among the common side effects in the UK product information
For study designs interrogating glucagon dynamics or gastric transit endpoints, the additive rather than redundant action across the two receptor arms is the point of methodological interest
No variants were identified in the SLC25A20 gene within the cohort, consistent with prior Illumina-based sequencing results, which did not detect any SLC25A20 mutation in these patients
It helps move fatty acids into mitochondria for energy
the authors explained that they then used propensity score matching based on whether the individuals received at least two prescriptions of a GLP-1 receptor agonist to create two comparable groups: one of 30,613 patients who had been prescribed a GLP-1 drug and one of equal size that did not