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4), particularly observed in thyroid cancer, indicates cancer development [75], given its role as a tumor marker in medullary thyroid neoplasia [86]
Each component has been independently studied for its potential roles in cellular protection, tissue remodeling, and biological regulation
7 Environmental factors play a role in this system, with sensory information fed into the central clock through signals from the eye, which are then converted to chemical signals in the SCN and synchronized with the peripheral systems