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But the official regulatory framework covers only the diabetes indication at this time

Non-selective c-Met inhibitors include crizotinib (PF-02341066), foretinib (XL-880), cabozantinib (XL-184), glesatinib (MGCD265), BMS-777607, and MK2461, which in addition to c-Met, can inhibit other tyrosine kinases, such as ALK, RON, VEGFR2, KIT, TIE2, PDGFR, VEGFR1, VEGFR3, RET, and FLT-3 [163,164,165], through binding to the ATP binding site on tyrosine kinases

The FDA is expected to release a verdict on or before Aug

Debaud C, Tseng H-W, Chedik M, Kulina I, Gent F, Ruitenberg M, et al

doi: 10.1152/physiolgenomics.00081.2016 142 VickersNJ