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blood can differ, with some examples showing a positive correlation, some showing lack of correlation, and some showing anticorrelation [e.g., (182186)]
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However, patients who lose significant weightwhether through medication, surgery, or lifestyle changesoften maintain a slightly lower metabolic rate than predicted for their new body weight
A 42-year-old female with longstanding profound fatigue, chronic pain, asthma, multiple food intolerances, GI symptoms including diarrhea, urticaria, food cravings, weight gain, and migraine who was essentially housebound due to constant exhaustion (she estimated 30% of normal energy) took tirzepitide at 3.75 mg principally to address obesity
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