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Researchers emulated a target trial using real-world data from a large, US-based, multi-centre electronic health record database to assess long-term outcomes of GLP-1RA use
While all carnitines remained stable under the first condition, free carnitine concentrations increased by 9.3 %-16.1 %, and certain acylcarnitines showed concentration decreases under the second condition, with most changes being less than 10 %
Whether it's an injection or a patch, it's part of a larger, medically-supervised system
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Providers may favor combination therapy if a patient tolerates GLP-1 well but requires additional glucose-lowering support without adding injectable medications or increasing GLP-1 dose further
