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Externally introduced arginase analogs can inhibit T cells antitumor activity by reducing the arginine level in the tumor microenvironment, just as the tumor or immunosuppressive cells expressing arginase 1 can

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High-Histamine Foods to Minimize During Challenging Seasons: Aged and fermented foods (aged cheese, sauerkraut, kombucha) Cured and processed meats (salami, bacon, deli meats) Leftover proteins (histamine increases as food sits) Certain vegetables: spinach, tomatoes, avocado, eggplant Vinegar and vinegar-containing foods Alcohol (especially red wine and beer) Foods That May Help: Fresh (not leftover) proteins: chicken, fish, beef cooked and eaten immediately Most fresh vegetables (except those listed above) Rice, quinoa, and other gluten-free grains Apples, pears, and most berries (good sources of quercetin) Fresh herbs: basil, thyme, oregano Taking probiotics that increase histamine production is a major overlooked contributor to elevated histamine levels and seasonal intolerance to pollen and pets