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The most sophisticated manufacturers further enhance purity through affinity chromatography, which utilizes specific binding interactions to capture glutathione while allowing impurities to pass through

Wang et al., 2020)

11 It is often administered as a weekly subcutaneous injection, but it can also be taken daily orally, as previously noted in Table 1

However, most of the reported GSH biosensors are expensive, time-consuming and often require complex sample treatment, which limit its biological applications