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Despite advances, including the use of pericytes and astrocytes in co-culture and simulation of the effects of shear stress in microfluidic models, we feel human BBB models could still be improved

Be patient and realistic about the expected results, and communicate regularly with your healthcare provider about your progress

FDA-Approved Drugs An FDA-approved drug has undergone an agency review of a specific product for defined uses, manufacturing controls, labeling, and an evidence package intended to support safety and effectiveness

pCT lacks sensitivity to detect subtle BBB alterations, e.g