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Notably, Johnson et al
TB-500 (Thymosin Beta-4 fragment): A synthetic actin-binding peptide researched for its roles in cell migration, actin sequestration, wound healing acceleration, and tissue remodeling
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Animal studies confirm its pro-regenerative profile across cutaneous, musculoskeletal, and vascular models
Compared to normal aging and D-GAL-induced premature aging models, research on endothelial cell senescence induced by hypoxia under pathological conditions remains scarce
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