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The key is to use the lowest effective volume and frequency to correct the deficiency or meet the metabolic need, and to adjust as the patients condition improves
The vial should remain sealed when not in use, and all withdrawals should be performed using appropriate sterile laboratory technique
For those following a vegetarian or vegan diet, or who are pregnant or nursing, an organized diet that includes food and drinks fortified with B12 is essential
If you have cirrhosis or creatinine clearance below 15 mL/min, alternative weight loss approaches may be safer pending more robust safety data in these populations
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