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Safety & Tolerability Preclinical Findings : IGF-1 LR3 demonstrates potent biological activity but requires strict dosing in experimental settings
The assumption of proportional hazards was evaluated with the generalized Schoenfeld approach on the TriNetX platform, with aHRs recalculated for specific time frames if initial assumptions were not met
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During a meal, this effect reduces the intestinal delivery of gastric contents resulting in a smaller glucose excursion, one of the mechanisms of action for diabetes therapeutic drugs 14
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