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In conclusion, the present study demonstrated that semaglutide promoted the proliferation and osteogenic differentiation of BMSCs through the Wnt/LRP5/-catenin signaling pathway, and proved that LRP5 may be a key factor in GLP-1 promoting osteogenesis, which has certain positive implications for improving BMSCs function in OP patients with T2DM
Allergic reactions, such as itching or redness at the injection site, can occur but are generally rare
It is important to continue following a healthy diet and exercise routine to sustain weight loss results achieved with the medication
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GoinesPECroenLABraunschweigDYoshidaCKGretherJHansenRet al
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