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Low dead space syringes reduce this waste significantly
And the zonula occludens proteins , ZO-1, ZO-2 and ZO-3, sit on the cytoplasmic face as scaffolds, linking the transmembrane components to the actin cytoskeleton which is how a junction can be actively pulled open rather than merely leaking
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and the GLP-1 drugs, semaglutide and tirzepatide
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