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Furthermore, disruption of GLS1 signalling using gene depletion or the use of the Gln inhibitor CB-839 will also lead to ubiquitination of c-MYC proteins, creating a GLS1-c-MYC positive feedback loop
Its not just about flooding the system
doi:10.1097/CRD.0000000000000513
Future studies are required to assess the absolute clinical impact of this potential side effect
While they may sound similar and sit in the same broad family of injectable metabolic medications, they are not the same thing
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