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However, the key is "gentle support." If the liver is pushed too hard, the "backlog" of metabolic waste can stress the heart

Based on the above results and our previous findings that inhibiting the cGAS-STING signaling pathway could suppress ferroptosis in skeletal stem cells derived from costal cartilage tissue [34], we hypothesized that GLP-1RAs might inhibit ferroptosis of chondrocytes by suppressing the activation of the cGAS-STING signaling pathway, and promote the synthesis of glycosaminoglycans and chondroitin sulfate, thereby alleviating the development of RA

However, its essential to acknowledge the limitations of our current hypothesis

Presented for research literature review only Pandey A et al