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Human umbilical cord blood-derived MSCs exosome attenuate myocardial injury by inhibiting ferroptosis in acute myocardial infarction mice
This metabolic shift also impairs mitochondrial complex I function and reduces mitochondrial membrane potential (m), priming the organelle for subsequent injury ( 2+ overload through activation of the mitochondrial calcium uniporter (MCU), further depolarizing m and triggering opening of the mPTP
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PMID 32446635
6f, p = 0.027)
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