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Incidences of other toxicities were comparable across the three treatment groups in DURATION-8 (exenatide plus dapagliflozin, exenatide alone, and dapagliflozin alone, respectively), including pancreatitis (1.3%, 0.4%, and 0%), volume depletion (1.3%, 0.4%, and 2.1%), gastrointestinal events (20.8%, 23.9%, and 16.3%), and genital infections (5.2%, 2.2%, and 7.7%) [36]
The six-month semaglutide injection plan works out to $150/month compared to $259 monthly
Other formats exist liposomal capsules, IV drips, even topical creams but their effectiveness can vary widely
If you are currently on semaglutide and considering a switch, see the semaglutide to tirzepatide conversion guide
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