According to a German study, metformin could make someone lose 5.8 kg on average over six months[9]
doi:10.18632/oncotarget.11168 Sakuma S, Ishimura M, Yuba Y, Itoh Y, Fujimoto Y
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Samples (30 g protein) were resolved by 420% SDS-PAGE (Biofuraw Precast Gel, Tanon Science, Shanghai, China), transferred to polyvinylidene difluoride membranes, and incubated with one of the following antibodies: LC3 (88588s, Cell Signaling Technology, 1:1000), GPX4 (ab125066, Abcam, 1:1000), p16 (1003-1-AP, Proteintech, 1:1000)