Clinical, Cosmetic and Investigational Dermatology , 10, 147-153
The goal here would be to lose weight while preventing sagging skin
These individual unimolecular multi-agonists activities seemed to harmonize the overall metabolic efficacy, which predominantly results from synergistic glucagon action to increase energy expenditure, GLP-1 action to reduce caloric intake and improve glucose control, and GIP action to potentiate the incretin effect and buffer against the diabetogenic effect of inherent glucagon activity
This hints at the peptide's potential to combat muscle atrophy under specific circumstances
More specifically, dietary supplementation with glycine helped to maintain a more reducing environment in all examined tissues (the liver, proximal intestine, head kidneys, tail kidneys, and skeletal muscle) except for the pancreas in both Phase-I and Phase-II HSB