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If retatrutide does not appear to be working as expected, the appropriate response is a structured review of your treatment plan not abrupt discontinuation or unsupervised dose escalation
If you are considering weaning off tirzepatide after achieving your weight loss goals, be aware that weight regain can reverse the metabolic improvements that protected against UTIs
When to stop Stop the protocol and contact your provider if you experience persistent redness or swelling at injection sites beyond 72 hours, fever, or any systemic symptom that does not correlate with the expected mild post-injection reaction
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