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Common signs include: Persistent and severe abdominal pain Tenderness in the abdomen Fever and chills Nausea or vomiting Constipation or, less frequently, diarrhea Risk Factors for Diverticulitis Several factors can increase the likelihood of developing diverticula or experiencing a flare-up

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Published findings describe effects on genes associated with antioxidant response (Nrf2 pathway), DNA repair mechanisms, ubiquitin-proteasome pathway components, and inflammatory signaling cascades