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Weight may stabilize if nutrition and exercise are well managed
10.1073/pnas.96.4.1569 Proc
For someone already close to frailty thresholds, a 1 to 2 kg hit to lean mass can dramatically reduce chair-stand time and raise the fall risk, which is why the quality of weight loss becomes extremely important in these patients
Post-adjustment, the filled random-effects meta-analysis calculated an effect size of 0.45 (95% CI: 4.385.28)
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