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In clinical practice, most reactions are related to technique, tissue sensitivity, or formulation not the peptide itself
Genetic variants in growth factor receptors and collagen regulation pathways should be interpreted with a qualified healthcare provider to understand individual tissue response potential
ARA-290 was well-tolerated in clinical trials with no serious adverse events
Importantly, folate supplementation should not be started before excluding B12 deficiency
doi: 10.1111/jocd.15763
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