It's often linked to the slower digestion these medications cause, which can lead to a general increase in sensory perception
In 2018, the recommendations of the international evidence-based guidelines for the assessment and management of PCOS [1] indicated that, although its use is generally off label, metformin can be considered in addition to lifestyle in women with PCOS and Body Mass Index (BMI) 25 kg/m 2 to potentiate weight loss and to improve endocrine and metabolic outcomes

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Collaboration in care model and patient education support offers an important lifestyle change, and providing ongoing support can enhance awareness and improve outcomes among communities
Due to rapid degradation by DPP-4 (Dipeptidyl peptidase 4), the half-life of endogenous GLP-1 is very short