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However, following the March 2026 patent expiry in India, China and Canada, licensed manufacturers are now legally producing and supplying generic versions at significantly lower prices
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Immunosuppressants contribute to serious infections, increase the risk of cancers (especially skin, liver, lymphoma, and kidney), lead to cardiovascular toxicity, and result in hospitalizations and complications [212,213,214,215]
Healthcare providers can adjust treatment plans and modify dosages if needed
Watch for signs of degradation: Discard if cloudy, colored, crystallized, or viscous, or if injection sites show redness, swelling, or pain
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