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Description

T2DM is a chronic, low-grade inflammatory disease characterized by elevated blood glucose and is regulated by a combination of genetics and environment

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Since the discovery and functional verification of GLP-1 in the 1980s ( However, the therapeutic utility of native GLP-1 was limited by its rapid enzymatic degradation and short plasma half-life, which prompted the development of longer-acting receptor agonists

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doi: 10.3109/00365599.2011.585622 233

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