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Higher attained dose during the pre-landmark period was associated with lower post-landmark cardiovascular risk Patients who reached high-dose semaglutide during the pre-landmark period (1.7 mg

Cell Metab (2018) 27(4):74056

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This mechanism is called the carnitine shuttle, in which fatty acids cross the mitochondrial membranes bound to L-carnitine, forming acylcarnitine molecules that can cross the mitochondrial membrane through a transporter in exchange for free L-carnitine