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Regulation of plasma histamine levels by the mast cell clock and its modulation by stress
Researchers have demonstrated plasma concentrations of CAIs after its topical use,6 which could be explained as topical CAIs are systemically absorbed through the nasopharyngeal mucosa or conjunctival blood vessels.5,6 Therefore, topical CAIs could potentially trigger severe and fatal cases of SJS and TEN in relatively young and healthy patients
Martinez HR, et al
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(2017, December 1)
