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"There's nothing in the current evidence that raises unique safety red flags" beyond the known GLP-1 side effects and risks, says Srivastava
The copper binds via the histidine imidazole ring, the peptide backbone, and deprotonated amide nitrogens, forming a stable, square-planar coordination complex
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Cases of IEC-EC have been reported since the drug was approved in 2022
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