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doi: 10.2174/187221312802652839 26 OkayamaY
3
Increased intracellular calcium inhibits enzymes responsible for the distribution of phospholipids in plasma membranes and the release of cytochrome C and apoptosis-inducing factors, triggering neuronal apoptotic death, suppressing neurotransmission, and cognitive dysfunction (Bezprozvanny and Mattson 2018)
In order to define suitable linkers for successful ADCs, the linkers must maintain high stability to ensure the integrity of ADCs in the blood circulation before reaching the tumor cells
5-Amino-1MQ appeared to work by increasing the energy expenditure of the fat cells themselves
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