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In terms of molecular mechanism, we also discussed the role of endogenous (enzymatic, and non-enzymatic) and exogenous antioxidants (vitamins, plant-derived and other small molecules), including ascorbic acids, -carotene, -tocopherol, -lipoic acid, coenzyme Q10, melatonin, and flavonoids (quercetin, luteolin, kaempferol, epicatechin, catechin, daidzein, genistein, and rutin, etc.) in scavenging of ROS
Lack of historical evidence to support folic acid exacerbation of the neuropathy caused by vitamin B12 deficiency
Jonathann Kuo, MD
Lack of glutathione contributes to oxidative stress, which plays a key role in lung disease, osteoarthritis, cataracts, glaucoma, chemotherapy, and cancer, as well as Alzheimers and Parkinsons disease