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The ER maintains a higher GSSG:GSH ratio than the cytosol
Samiec PS, et al
The cells were then stimulated with 0.5 mM H 2 O 2 for 24 h, and the number of cells was determined with a Cell Counting Kit-8 (Dojindo) according to the manufacturers protocol
ZMYND8 cooperates with the transcription factor FOXM1 to bind critical genomic loci and recruit the SWI/SNF chromatin remodeling complex, thereby activating neuroendocrine gene expression programs and promoting lineage plasticity that contributes to therapy resistance
Their biological mechanisms complement one another
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