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ChaC1 serves as a reliable indicator for poor prognosis of certain types of gastric cancer (63) and melanoma (75,76), as well as an independent indicator for elevated risk for female germ line tumors (including breast and ovarian cancer) (77)
Zo is misselijkheid en hoofdpijn niet fijn, maar hoeft het niet direct ernstig te zijn
Clinical trial data shows that up to 50% of participants experienced some form of abdominal distension during treatment, with symptoms most pronounced during dose escalation and the early weeks
Additionally, the N-terminal extension may partially shield protease-sensitive sites on the IGF-1 backbone from insulin-degrading enzyme (IDE) and other endopeptidases