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Pirard-Franchimont C1, De Doncker P, Cauwenbergh G, Pirard GE
Key points The weight loss induced by glucagon-like peptide receptor 1 agonists (GLP1RAs) should reduce the risk of some malignancies, although stimulation of GLP1 receptors might have either detrimental or beneficial direct effects on cancer risk
The already recognized roles of GSTs are the detoxification of toxic substances by their conjugation with glutathione, the attenuation of oxidative stress and the participation in hormone transport
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Structurally unique GLP-1-based medicines that achieve substantially greater and rapid weight loss may impact musculoskeletal health, providing a rationale for therapeutics that more selectively target adipose tissue loss while preserving muscle mass and strength
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