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This matters because much of the public buzz around these medicines is about weight loss, while many early launches may be positioned first through the diabetes route
Worth a read for anyone following obesity care and real-world evidence: To view or add a comment, sign in A diagnostic paradox buried in the Lancet obesity framework: Patient A: HbA1c 6.1% + dyslipidemia meets definition of "clinical obesity" Patient B: HbA1c 6.8% (diagnosed T2DM) + normal lipids may not qualify as "clinical obesity" T2DM was excluded from the organ-dysfunction criteria despite: ~90% of T2DM patients being overweight or obese Strong mechanistic links to visceral & ectopic fat ~50% diabetes remission rate with intensive weight loss at 1 year This inconsistency may create real coverage and access problems
95% CI, 8.84 to 2.99
Pulsatile GH secretion 3 (regular hormone pulses) is preserved with CJC-1295, and both basal and mean GH are significantly increased within one week of treatment
Primary Care Physicians Many people begin their weight-loss journey with their existing primary care doctor
