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The MHRA's Summary of Product Characteristics (SmPC) for Ozempic acknowledges these gastrointestinal effects as expected consequences of GLP-1 receptor agonism

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Implementation of the reforms was staged over 3 years

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Researchers compared outcomes with users of another weight loss drug, bupropion-naltrexone (n = 654), and monitored all patients for development of biliary disease, pancreatitis, bowel obstruction or gastroparesis

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