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[1] Tirzepatide acts through two incretin receptors at once , GIP and GLP-1, adding a glucose-dependent insulin-secretion effect that an amylin analog does not have

doi: 10.3389/fnut.2025.1650929 Received 20 June 2025 Accepted 29 September 2025 Published 20 October 2025 Volume 12 - 2025 Edited by Biao Zhang, Dalian Medical University, China Reviewed by Matias Caverzan, National University of Ro Cuarto, Argentina Diogo Estvo, Universidade do Porto, Portugal Updates Copyright 2025 Lin, Yin and Guan

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10.1016/j.ejphar.2019.172593 137 TabataY.NaganoA.IkadaY