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Additionally, any symptoms of severe gastroparesis or intestinal obstruction (severe abdominal pain, persistent vomiting, or inability to tolerate oral intake) warrant immediate medical evaluation

In this study, Sprague-Dawley rats were administered with homocysteine neonatally from postnatal day 2 and then monitored until adulthood

The authors concluded that once-weekly tirzepatide induced superior glycaemic control compared with daily insulin degludec in adults with T2DM treated with metformin, with or without an SGLT2 inhibitor

Concurrent medications (metformin, PPIs, antibiotics) and underlying gastrointestinal conditions may cause diarrhoea coinciding with B12 supplementation

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