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Supplementary Information 12876_2026_4664_MOESM1_ESM.xlsx (download XLSX Supplementary Material 1
Hydrolyzed type I, III bioactive peptides
Generally, the synthesis of melanin is a complex process, with a multitude of genes influencing its production, such as tyrosinase-related protein 1 ( TRP-1 ), glycogen synthase kinase-3 beta ( GSK3 ), -catenin , cyclic adenosine monophosphate ( cAMP ), cAMP-response element binding protein ( CREB ), and solute carrier family 7 member 11 ( SLC7A11 ) [93, 185, 228]
Conclusion BPC-157 stands out as a peptide with substantial potential for promoting tissue repair, reducing inflammation, and possibly improving gut health
This represents approximately 3-fold improved local delivery and demonstrates that formulation significantly impacts outcomes
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