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Therefore, having a healthy and balanced gut microbiome is essential for optimal methylation.4 These conditions can also interact and create a vicious cycle that worsens your methylation and health
Figure 1 Whilst much attention was focused on GLP-1 in the 1980s and 90s, following the discovery of its incretin effect in humans (21), little was known about the physiological role of oxyntomodulin in humans at the time (21, 22)
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