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Other factors that may increase infection risk in diabetes patients include: Immunosuppressive effects of poorly controlled hyperglycemia Neuropathy leading to reduced sensation and delayed recognition of infections Vascular complications impairing tissue perfusion and immune cell delivery Frequent antibiotic use for other infections, disrupting normal flora Obesity , which is common in type 2 diabetes and creates skin folds prone to moisture and fungal growth Conversely, medications that improve glycemic control, including GLP-1 receptor agonists and tirzepatide, generally reduce infection risk by normalizing the metabolic environment

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GLP-1 receptor agonism is associated in the research literature with modulation of satiety signaling and energy expenditure, underpinning much of the weight reduction focus in Retatrutide study designs

Patients appreciate avoiding long wait times and in-person clinic visits, receiving medications shipped directly to their door, and having telehealth appointments that fit into their busy schedules