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Hierarchical shifts in gut microbiota composition Family-level analysis (Figure S1A) confirmed pronounced dysbiosis in the VPA-ASD group, which was enriched with pathogenic families such as Clostridiaceae and Erysipelotrichaceae and exhibited severe depletion of beneficial families including Muribaculaceae

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Clinically, the U-shaped curve illustrates the risks associated with excessive antioxidant supplementation in the absence of proper professional oversight and individualized patient assessment [23]

The 3 amino acids in this copper peptide create a specific binding site that has high affinity for copper ions

JAMA 1984;252:1443