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typically transient Flushing : Facial flushing reported in a significant minority of patients Headache : Reported at higher rates than placebo Blood pressure : Transient increases in blood pressure noted

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The more reasonable conclusion is that these channels are where patients who would otherwise not qualify to receive the drugs they are seeking are funneled (which was the case 100% of the time in this study)

doi:10.1016/j.jaccao.2019.10.006 22