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Of course, were still early: Most studies are small or preclinical Larger clinical trials are needed Access, cost, and safety must be considered But this could represent a real shift in how we think about treating addiction not just as a behavioral condition, but as one deeply tied to metabolic and brain pathways

In the SURMOUNT-1 trial, adults taking injectable tirzepatide lost an average of about 15% with the 5 mg dose, 19.5% with the 10 mg dose, and 20.9% to 22.5% with the highest 15 mg dose after 72 weeks

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J Neuroinflammation 16

Retrieved from Drucker, D