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Our choice of metformin as a proof-of-concept test as a CI inhibitor 79 in these orthotopic models was based on several factors: (1) it could easily be taken forward safely into in vivo studies with known target concentrations
M.HartmannB.et al (2015)
A randomized double-blind, placebo-controlled trial with eighty participants aged 21 to 65 found that daily supplementation for five weeks improved perceived recovery and reduced soreness
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Type III tests of fixed effects were conducted using the car package 86 to evaluate the statistical significance of main effects and interaction terms
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