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The mechanism of action involves several complementary pathways: Enhanced insulin secretion : GLP-1 agonists stimulate glucose-dependent insulin release from pancreatic beta cells, meaning insulin is only released when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia
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These differences can affect how patients respond to treatment, how dosing is managed, and what type of weight loss results are achievable over time
- Muscle loss is a real issue too, as these drugs can hit lean mass hard
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